|
overview | current openings |
employee profiles
Senior Scientist, Chemistry
- CH1
Agios Pharmaceutcals (www.agios.com) in Cambridge, Massachusetts, is
the first biopharmaceutical company dedicated to drug discovery based on targeting cancer metabolism, which offers the potential for a new class of
oncology therapeutics targeting metabolic pathways critical to cancer cell
growth, proliferation and survival. With new research showing that cancer cells
become addicted to using more nutrients than normal cells to promote their rapid growth, there is an unprecedented opportunity to create a new class of oncology therapeutics that target a fundamental and ubiquitous mechanism in cancer
cells. The intersection of these two fields of research – cancer and metabolism- represents an important and novel approach to treating cancer. This new understanding of a fundamental mechanism of cancer survival represents
a new and powerful Achilles’ Heel to target this deadly disease.
Agios is developing novel drugs that will primarily target three key
metabolic pathways — glycolysis (sugar metabolism), fatty acid metabolism,
and autophagy (self-metabolism). The founders’ scientific insights, and the expertise and guidance of the Company’s Scientific Advisory Board and Management, drive the company’s mission of developing a deep pipeline of therapeutics to treat cancer in a completely new and fundamental way —
through blocking their fuel, causing the cells to ‘starve to death.’
The Company is focused on achieving rapid and clinically significant human
proof of concept and on building a deep and diversified product pipeline
designed to target the metabolic pathways responsible for the growth and
survival of cancer cells.
Qualifications
-
The successful candidate will have a PhD in Organic Chemistry and 7-10 years of relevant pharmaceutical industry experience.
-
Strong organizational and communication skills are a must.
-
The candidate will have demonstrated strong leadership skills and a track record of success in all aspect of drug discovery from hit identification, hit to leads and especially in lead optimization to defined clinical candidates.
-
Experience in utilizing cross-functional information, such as cellular data and ADME/DMPK, to drive medicinal chemistry strategies is a must.
-
The candidate will have demonstrated a history of strong managerial skills both in managing chemistry groups in a line function as well as experience in functioning within a matrix driven organization.
-
Experience in managing external FTE resources in chemistry is a plus.
A competitive compensation package as well as benefits will be offered.
Agios is committed to the diversity of all great ideas and great people.
To apply please submit your resume and cover letter to job_opportunities@agios.com.
We will respond directly if there is interest.
Thank you for considering Agios.
[ ]
|
